BPC-157 is a partial sequence of body protection compound (BPC) found in human gastric juice. It has been researched to see if it can accelerate healing of a variety of wounds including tendon-to-bone healing and healing of damaged ligaments. Research has studied a potential protective effect against gastric ulcers. It has been studied for protection of the liver from toxic damage (alcohol, antibiotics, etc.). Lastly, it has been studied for healing of traumatic brain injury (TBI). BPC-157 has been researched to: Improve healing of many types of wounds – Protection of intestinal organs and prevention of stomach ulcers – For combat of leaky gut, IBS, gastrointestinal cramps and Crohn’s disease – Accelerated healing of skin burns – As an anti-inflammatory – Integrity of mucosal lining GI tract – Repair of tissues of GIT, tendons, ligaments, brain, bone, etc. – Improve of digestive function – Protection and promotion of healing of liver due to toxic stress.
RESEARCH:
In response to tendon and ligament injury, BPC-157 supports healing by increasing type 1 collagen in these tissues. BPC-157 is cytoprotective and thus helps maintain the mucosal lining of the GI tract. As an anti-inflammatory, it supports the protection and healing of inflamed intestinal tissues. It also may play a role in tissue damage repair by increasing blood flow to damaged tissues. BPC-157 is stable in human gastric juice and has no reported toxicity.
DISCUSSION
BPC-157 has been researched to:
- Improve healing of many types of wounds
- Protect intestinal organs and prevents stomach ulcers
- Combats leaky gut, IBS, gastrointestinal cramps and Crohn’s disease
- Accelerate healing of skin burns
- Work as an anti-inflammatory
- Maintains integrity of mucosal lining GI tract
- Repair tissues of GIT, tendons, ligaments, brain, bone, etc.
- Improve digestive function
- In response to tendon and ligament injury, BPC-157 supports healing by increasing type 1 collagen in these tissues. BPC-157 is cytoprotective and thus helps maintain the mucosal lining of the GI tract. As an anti- inflammatory, it supports the protection and healing of inflamed intestinal tissues. It also may play a rolein tissue damage repair by increasing blood flow to damaged tissues. BPC-157 is stable in human gastric juice and has no reported toxicity.
SNAC
SNAC is added to BPC-157 PRO in order to increase stomach and intestinal permeability. SNAC helps with bioavailability of oral absorption of peptides
such as BPC-157. SNAC is considered to be safe for human consumption (GRAS) by the FDA.
REFERENCES
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- Sikiric P, Seiwerth S, Rucman R, et al. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. doi:10.2174/1570159×13666160502153022
- Chang CH, Tsai WC, Lin MS, Hsu YH, Pang JH. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell
migration. J Appl Physiol (1985). 2011;110(3):774-780. doi:10.1152/japplphysiol.00945.2010 - Gwyer D, Wragg NM, Wilson SL. Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. Cell
Tissue Res. 2019;377(2):153-159. doi:10.1007/s00441-019-03016-8